![]() In other older works increasing sexual frequency did appear to increase fecundability in patients recording conception and basal body temperature, although semen characteristics were not assessed in these studies ( 6, 7). One would suspect that if sperm counts remain stable with daily ejaculation during these optimal days of conception, then pregnancy rates could be optimized by frequent intercourse, as more total sperm would be available for conception. Interestingly, authors did not find that frequency of intercourse decreased the probability of conception ( 3) despite older studies that suggest overly frequent ejaculation may be detrimental to sperm counts ( 4, 5). In their influential report from the 1990s, investigators found that conception occurred most frequently when intercourse occurred on either the 2 days before ovulation or the day of ovulation ( 3). In the joint committee opinion paper from the American Society of Reproductive Medicine and Society for Reproductive Endocrinology and Infertility timed and frequent intercourse around the time of female ovulation is recommended but does not make more specific comments ( 2). The 1999 WHO guidelines recommended a 2–7 days period of abstinence prior to providing a semen sample for laboratory analysis ( 1) but does not otherwise comment on how the frequency of ejaculation may affect semen analysis parameters or conception outcomes. The effect of frequency of ejaculation on semen characteristics is an important clinical question with obvious connections to conception rates. Keywords: Semen analysis DNA damage sperm quality counseling male factor infertility These findings generally support an approach of a short period of abstinence followed by daily copulation around ovulation to maximize the number of sperm available and optimize conception. Metrics of DNA integrity did not change in a statistically or clinically meaningful way during the study period.Ĭonclusions: While a small study, this represents the most extensive examination of sperm quality with daily ejaculation. ![]() A large initial change in ejaculate volume, TMC and sperm concentration provided the primary difference in these values over the study period, with a plateau in values after this initial decrease (after study day 3). Significant decreases were observed in mean semen volume, total motile count (TMC) and sperm concentration during the study period without significant changes in motility or morphology. Results: The mean age of men completing the study was 25 years (range, 23–33 years). In addition to the standard semen analysis, markers of sperm DNA quality were assessed. Semen samples were collected at the beginning of the study (day 1) and then on days 3, 7 and 14. Methods: Twenty normal men were recruited for daily ejaculation over 14 consecutive days, after a 3–5 days abstinence period. Although a significant number of articles have examined how the length of abstinence affects these semen analysis, the effects of frequent (daily) ejaculation has not been rigorously studied. Köhler 5ġDivision of Urology, Albany Medical College, Albany, NY 12208, USA 2Albany Stratton Veterans Affairs Medical Center, Albany, NY 12208 USA 3The Urological Institute of Northeastern New York, Albany, NY 12208, USA 4OSF Healthcare, Peoria, Illinois 61615, USA 5Division of Urology, Southern Illinois University School of Medicine, Springfield, IL 62794, USA 6Division of Clinical Research, ReproSource Inc., Woburn, MA 01801, USA 7Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, NY 12208, USA 8Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62794, USAĬontributions: (I) Conception and design: AD Benson, TS Köhler (II) Administrative support: AD Benson, L Frederick, B Leader, M McAsey, TS Köhler (III) Provision of study materials or patients: AD Benson, L Frederick, J Kontio, M McAsey, TS Köhler (IV) Collection and assembly of data: C Welliver, AD Benson, L Frederick, B Leader, E Tirado, P Feustel, M McAsey, TS Köhler (V) Data analysis and interpretation: C Welliver, AD Benson, L Frederick, B Leader, E Tirado, P Feustel, TS Köhler (VI) Manuscript writing: All authors (VII) Final approval of manuscript: All authors.īackground: Timed and frequent intercourse around the time of female ovulation is recommended to improve conception. Benson 4, Luke Frederick 5, Benjamin Leader 6, Edna Tirado 6, Paul Feustel 7, James Kontio 8, Mary McAsey 8, Tobias S. Policy of Dealing with Allegations of Research MisconductĬharles Welliver 1,2,3, Aaron D. ![]()
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